What is Peripheral Arterial Disease?
Peripheral arterial disease (PAD) is a circulatory disorder characterized by narrowing of the blood vessels, usually in the legs. The condition is usually caused by atherosclerosis, a buildup of plaque (fatty substances) along the inner wall of the arteries. In this way, it is very similar to coronary artery disease, except that a different region of the body is affected. Blood clots can also form and cause similar symptoms. PAD affects as many as 12 million people in the United States.
 What are the Symptoms of PAD?
This narrowing, or stenosis, restricts proper blood flow through the affected arteries, resulting in what is known as limb ischemia. Patients often experience leg pain, especially during exercise, a condition called intermittent claudication. Since oxygen travels around the body through the blood, the pain is caused because not enough oxygen can reach the muscles and surrounding tissue during periods when it is needed, such as during exercise.
In patients with occasional symptoms, the pain often disappears after a few minutes of rest. However, the condition can become chronic and cause persistent pain, even when resting. Fortunately, various treatments can help alleviate these symptoms. Common signs and symptoms of PAD include:
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Pain in the legs or feet that disturbs sleep
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Cramping, heaviness, fatigue in leg muscles that occurs during activity, but goes away when the activity stops
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A lower temperature in one leg compared to the other
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Poor nail or air growth on toes and legs
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Changes in color to the skin of the feet, including paleness or blueness
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Sores or wounds on toes, feet or legs that heal slowly, poorly, or not at all
Most people with PAD do not experience symptoms at all; this is why it is important that you and your doctor consider all your risk factors.
What is my Risk for PAD? 
Risk Factors Include:
PAD puts you at increased risk for Heart Attack, Stroke, Aneurysm, and Loss of Limbs.
How is PAD Detected?
A Vascular Specialist will use non-invasive testing to determine the presence and level of arterial disease. To detect PAD in the legs, the most common method of disease detection is ABI, or Ankle Brachial Index. ABI tests the quality of circulation in the legs by comparing the systolic blood pressure in the ankle to the systolic blood pressure in the arm. A blood pressure at the ankle that is lower than the blood pressure at the arm suggests the presence of disease, or narrowing of the arteries due to plaque build-up.
If the blood pressure in the leg is less than half the blood pressure in the arm, your doctor may suggest more advanced diagnostic testing to determine the level and exact location of the arterial blockage, or your doctor may suggest intervention.
What are the Treatment Options for PAD?
Medication, exercise, quitting smoking, and other therapies may help patients with occasional symptoms and intermittent claudication. But for patients who experience persistent pain when resting, ulcers, gangrene, or severely limited activity as a result of PAD, revascularization is often the only solution. Intervention can prevent the symptoms and disease from worsening-in very extreme cases, PAD can progress to the point that amputation is required.
Depending on the severity and length of the blockage, different treatments may be prescribed. For localized blockages, angioplasty and/or stents may correct the problem. For longer segments of blockage, bypass is usually recommended. In either case, the procedures are similar to those used to treat coronary arteries on the heart.
Bypass Illustration
What Takes Place During Treatment?
For relatively small blockages, angioplasty is often an effective treatment. A catheter with a balloon device attached is inserted in the arteries, and the balloon is inflated to stretch open the narrowed artery. This allows blood to flow more easily through the artery throughout the leg or other extremity. A stent (a small metal cage device) may be placed in the artery to help keep the vessel open once the balloon is removed. These procedures can be done as an outpatient-recovery is rapid.
When angioplasty and stent placement can not be done, a surgical bypass of the blockage is another option. The bypass may be a vein from your own body (usually the leg) or made of synthetic material. The surgeon attaches the graft to the diseased artery on either side of the blocked area. This creates a new channel through which the blood can flow and allows oxygenated blood to travel to the leg and foot below the blockage, thus reducing or eliminating the pain associated with PAD in addition to the amputation risk.
Recovery following a surgical revascularization usually includes about one week in the hospital. Since this is a relatively invasive procedure, full recovery may take six to eight weeks.
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